Fare thee well!!

My best friend is leaving me!! She got a promotion a few days ago. I have to admit, it is a wonderful offer. What is so not wonderful about it is , if she decides to accept it, she will have to go to Kolej Matrikulasi Pahang in Gambang. Somehow, if she's not here anymore it won't be the same. Sometimes we are so attuned to one another that we don't have to say it out loud. We really can understand each other's thoughts and feelings. That is the degree of our closeness. I know this separation from her husband and  family will make her sad. The word sad is not really appropriate in this context. Is there one word that means sad, devastated, teary eyed and miserable? Does it have to come to this? Why are they so blind to our plight? Aren't they someone else's husband, wife, son and daughter too?